Mendoza is by far the largest wine region in Argentina. Located on a high-altitude plateau at the edge of the Andes Mountains, the province is responsible for roughly 70 percent of the country's annual wine production. The French grape variety Malbec has its New World home in the vineyards of Mendoza, producing red wines of great concentration and intensity.

The province lies on the western edge of Argentina, across the Andes Mountains from Chile. While the province is large (it covers a similar area to the state of New York), its viticultural land is clustered mainly in the northern part, just south of Mendoza City. Here, the regions of Lujan de Cuyo, Maipu and the Uco Valley are home to some of the biggest names in Argentinian wine.

This soil in this region is alluvial with rocky subsoil. It possesses sediments of sand, silt and clay. Its little organic matter restraints the grapevine’s growth and this results in excellent quality grapes suitable for winemaking. Malbec wines from this area hold outstanding features; red and violet tones with great intensity.